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Science:不应对原生动物的引起疾病忽视

摘要 : 世界卫生组织列出的17种被忽视的热带疾病,三种是由寄生于原生动物的病毒引起的:非洲人的锥虫病(HAT;也被称为昏睡病),利什曼病和锥虫病。

 世界卫生组织列出的17种被忽视的热带疾病,三种是由寄生于原生动物的病毒引起的:非洲人的锥虫病(HAT;也被称为昏睡病),利什曼病和锥虫病。这三疾病在世界最贫困人群中表现出高发病率和死亡率。尽管这些和其他被忽视的疾病在过去的十年中已经受到越来越多的关注,新的药物仍然是稀缺的:从2000到2011,新的药物和疫苗,只有4%被列明为被忽视的疾病所用。然而,药物开发路上,持续的资源和研究的努力,在未来的十年,应该看到新的药物传递给这些疾病。

原文链接:

Overcoming neglect of kinetoplastid diseases

原文摘要:

Of the 17 neglected tropical diseases listed by the World Health Organization (WHO),three are caused by parasitic kinetoplastid protozoa: human African trypanosomiasis (HAT; also known as sleeping sickness), leishmaniasis, and Chagas disease. The three diseases are responsible for high mortality and morbidity among the world's poorest populations. Although these and other neglected diseases have received increased attention over the past decade, new drugs are still scarce: From 2000 to 2011, only 4% of new drugs and vaccines were registered for neglected diseases. However, the drug development pipeline, with sustained resources and research efforts, should see the delivery of new drugs for these diseases over the next decade.

来源: Science 浏览次数:0

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